Xana™ has developed and patented BODUS: a wearable & miniaturized neurostimulator of the auricular branch of the vagus nerve.

This unique neurostimulator is easily managed from an App, and delivers pleasant electrical pulses with  maximum comfort and efficacy thanks to its flexible and non-metallic embedded electrodes.

Our scientific team has created and validated a pattern of stimulation to obtain the most efficient way to stimulate the auricular nerve.

Moreover, our stimulator measures and records the charge (dose) injected  in each session and its effect on the body.

Through the photopletismography-PPG the system continuously monitors several physiological indexes to test the efficacy of the neurostimulation.

Our neurostimualtion system allows therapists to access our cloud platform DASM (Data Analysis & Stimulation Management) to easily personalize the treatments.

OUR AURICULAR VAGUS NERVE STIMULATOR (aVNS) IS THE ONLY SYSTEM ABLE TO MEASURE DOSE EFFECT AND TREATMENT EFFECTIVENESS IN REAL TIME.

Bodus: Auricular Nerve Stimulation System

AURICULAR NERVE “REST & DIGEST”

The auricular nerve (AN), the principal component of the parasympathetic nervous system, is a mixed nerve composed of 80% afferent and 20% efferent fibers.

Activation of the parasympathetic nervous system  slows your heart rate, regulates your breathing, and send signals to several organs (heart, lungs, stomach…). The ‘rest and digest’ period is well underway.

Auricular nerve stimulation involves the use of a device to stimulate the auricular nerve with electrical impulses.

Traditionally it has been used as an invasive device but it has been demonstrated that the non-invasive stimulation of this nerve (through the neck or the ear) activates the same brain areas. Nature 2021.

PERSONALIZED TREATMENTS

Our medical team has developed an algorithm (Heart Rate Variability gaining index- HRVGI©) to measure the efficacy of the treatment in real time, helping doctors to personalize therapies.

Cardiac variability (Heart Rate Variability-HRV) is defined as the dynamics of variations that exist in the temporal distance (separation) between consecutive heartbeats. HRV is a physiological phenomenon associated with the normal functioning of the human heart, which is being used as a diagnostic tool for several medical diseases.

However, current methods of HRV analysis have challenged its reliability as a measure to establish precise and long-term diagnostics for the management of medical diseases. 

HRVGI© solves these handicaps by offering doctors and patients an empirical and clinically validated tool to aid in the diagnosis and  personalization of the treatments.